Uridine 5'-diphospho-glucuronosyltransferase (UDP -glucuronosyltransferase, UDPGT or UGT) is a microsomal glycosyltransferase (EC 2.4.1.17) that catalyzes the transfer of the glucuronic acid …

UDP-glucuronosyltransferases (UGTs) are phase II drug-metabolizing enzymes that metabolize endogenous fatty acids such as arachidonic acid metabolites, as well as many prescription drugs, …

All UGT genes that have been named by the committee and associated publicly available information are available for download. The latest publicly available UGT names and sequences (up until 11 …

Uridine diphosphate-glucuronosyltransferase, or UGT, is a family of enzymes essential for detoxification. These specialized proteins act as the body’s internal cleanup crew, ensuring that both internally …

Results are interpreted for the purposes of UGT1A1 drug metabolism and hereditary hyperbilirubinemia syndromes (Gilbert syndrome and Crigler-Najjar syndrome). This test does not include …

UGT, or glucuronosyltransferase, is defined as a Phase II enzyme that facilitates drug metabolism by covalently adding a glucuronic moiety to drugs or endogenous compounds. The major isoforms …

This review discusses recent advances in the understanding of the functional roles of UGT, their regulation and tissue expression, and clinical significant factors (ontogeny, interactions and …

UGT-1A is a uridine diphosphate glucuronosyltransferase (UDP-glucuronosyltransferase, UDPGT or UGT), an enzyme of the glucuronidation pathway that transforms small lipophilic (fat-soluble) …

Jul 23, 2025 · UDP-glucuronosyltransferase (UGT) enzymes are a family of proteins that play an important role in the body’s detoxification processes. These enzymes are found predominantly in the …

UGT, or glucuronosyltransferase, is defined as a family of microsomal membrane-bound enzymes that catalyze the conjugation of bilirubin, steroids, bile acids, and xenobiotics with UDP-glucuronic acid.