The cell cytoskeleton is modulated by motor proteins, known as dyneins, that generate force and movement on microtubules to control a wealth of biological processes, including motility, cell division, ...

The kinesin-2 motor protein uses a hook-like adaptor and cargo-binding (HAC) domain to recognize and transport cargo along microtubule highways, revealing a cellular logistics system critical for ...

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This process is especially important in neurons, which have highly polarized ...

Salk Institute and UC San Diego researchers capture first-of-its-kind video of dynein-Lis1 protein interaction, supporting future drug development for neurological disorders LA JOLLA (May 23, ...

Researchers use hIL-6 protein to restore walking in paralyzed mice by promoting neural circuit plasticity rather than fiber regrowth.

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This process is especially important in neurons, which have highly polarized ...

Manganese is not a metal most people think much about. Unlike lead or mercury, it has a benign reputation. Small amounts of ...

Scientists traced connectivity between neurons to identify how the brain communicates with the spinal cord to control motor function. Signals relayed to motor neurons from the brain enable muscle ...

New connections begin to form between brain cells almost immediately as animals learn a new task, according to a study published this week in Nature. Led by researchers at the University of California ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...

The brain’s immune cells are supposed to devour the sticky amyloid plaques that accumulate in Alzheimer’s disease. In ...