Flow cytometry offers practical advantages for real-time monitoring of CAR T cell expansion, persistence, and toxicity risk in aggressive large B-cell lymphoma patients. Early CAR T cell expansion is ...
Cytotoxicity is a broad term that refers to the negative effects of chemical or environmental changes on cell health. Cells exposed to a cytotoxic stimulus may lose metabolic activity, experience ...
Not all patients respond well to chimeric antigen receptor (CAR) T cell therapies, which reprogram a patient’s own immune cells to recognize and attack cancer. A way to optimize these treatments is to ...
CAR-T translational research demands precise, reproducible, and scalable flow cytometry workflows. Manual centrifugation and antibody preparation steps remain major sources of variability and cell ...
As interest in CAR T cells and immune-based oncology therapies increases, efficient phenotyping of cell therapy products becomes more crucial. Because this process involves analyzing surface markers ...