Visualization in the UMAP space of samples corresponding to the subtypes ER+ (a), HER2+ (b), and TN (c). The samples were categorized by cancer subtype and integrated. Cells are color-coded according ...

Despite major advances in targeted therapies, immunotherapies, and combination regimens, therapy resistance remains a central barrier to durable cancer ...

Deck Bio today launches with a multi-target approach designed to expand the reach of T cell engagers in solid tumors by addressing tumor heterogeneity and resistance. Founded by Jack Silberstein, Ph.D ...

Colorectal cancer is the third most commonly diagnosed cancer worldwide and the second leading cause of cancer death, yet one ...

Super-enhancers (SEs) are large clusters of transcriptional regulatory elements that drive oncogene expression, maintain ...

Despite substantial progress in cancer treatment, durable benefit is still frequently limited by the ability of tumors to adapt under therapeutic pressure.

Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...

For his work towards developing a novel cancer immunotherapy that turns tumors into their own vaccines, Fábio Rosa has received the 2026 BioInnovation Institute & Science Prize for Innovation. The ...

Glioma is a tumor of the central nervous system that originates from glial cells, which support neurons in the brain. In the ...

Glioblastoma is one of the most aggressive brain tumors, with poor survival rates and limited treatment options. Standard ...