This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Researchers at the University of California San Diego and the Veterans Affairs San Diego Healthcare System have identified a ...

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect against ...

There were no serious adverse events (SAEs) There were no treatment emergent adverse events leading to discontinuation of AK006 There were no dose limiting toxicities The most common adverse events ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

Immune cell trapping during allergic responses Mast cells, residing in tissues and critical for initiating inflammation, are filled with granules containing pro-inflammatory substances. These granules ...