In nature, evolution takes years to sculpt new traits. In the lab, scientists hope to achieve this feat much faster: Being able to evolve proteins with enhanced or novel functions has important ...
Schematic of the T7-ORACLE system. The genome is maintained by the non-mutagenic host replisome (gray), while an orthogonal T7 replisome (red) maintains only a dedicated plasmid (OR) at 100,000-fold ...
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