An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...

Carlsberg has developed a method using digital PCR to identify specific nucleotide mutations in mutated genes. The process involves random mutagenesis, dividing organisms into sub-pools, PCR ...

Using data to identify the genetic changes that cause healthy cells to become malignant can help doctors select therapies that specifically target the tumor. Most of the roughly 40 trillion cells of ...

Researchers at The University of Texas at Austin now have developed an improved method of gene editing that is precise, more efficient than other similar methods and can correct many disease-causing ...

A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...

Researchers have used advanced sequencing techniques to analyze immune cells in great detail. This work has shown that over the course of a lifetime, B and T cells can acquire a trove of genetic ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

Researchers have traced the cause of increased numbers of mutations in children to a higher rate of random mutations in sperm cells of the biological father, associated with rare genetic defects in ...