A polygenic risk score was able to detect a high proportion of clinically significant prostate cancer. Cancer would not have been detected in 71.8% of patients with the use of PSA or MRI screening.
La Gerche said studies show bradycardia, defined in the study as a heart rate ≤ 40 beats/min, and sinus pauses of 2-3 seconds ...
Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of ...
Please provide your email address to receive an email when new articles are posted on . Researchers developed a multi-ancestry polygenic score using data from two genome-wide association studies.
Breast cancer is the most frequently diagnosed cancer in women, accounting for over 15% of all new cancer cases in the United States. Abnormal cell growth in the breast ducts (DCIS) or lobules (LCIS) ...
Nearly all men with a polygenic risk score in the 90th percentile or above had a 10-year absolute risk for prostate cancer exceeding 3.8%. A polygenic risk score (PRS) identifies more patients with ...
Cardiovascular disease ("CVD") is the leading cause of death in the US and worldwide with over 82 million Americans living with CVD. CVD accounts for one in every three deaths in the US, or more than ...
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A polygenic risk score may predict future breast cancer in patients with early-stage diagnoses
A retrospective study found that the 313-SNP breast cancer polygenic risk score (PRS 313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in situ ...
A new genetic tool — called a polygenic risk score (PGS) — uses DNA data from over five million people to predict adult obesity risk from early childhood. The score explains about 17 % of BMI ...
Polygenic background bidirectionally modifies the penetrance of pathogenic variants in hypertrophic (HCM) and dilated (DCM) ...
“What makes the score so powerful is its ability to predict, before the age of five, whether a child is likely to develop obesity in adulthood, well before other risk factors start to shape their ...
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