Allelica, a leader in genomic risk assessment for common diseases, announced today that polygenic risk scores (PRS) have been recognized as a risk-enhancing factor in the 2026 American College of ...

Combining a polygenic risk score (PRS) with traditional biomarkers can help clinicians better estimate a patient’s risk of developing coronary artery disease (CAD), according to new UK Biobank data.

Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as ...

A retrospective study found that the 313-SNP breast cancer polygenic risk score (PRS 313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in situ ...

The results of research by scientists at University College London (UCL), Imperial College London, and the MRC Laboratory of Medical Sciences, indicate that a potentially life-changing heart condition ...

Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of ...

Early-onset (EO) cancer trends in Brazil: A comprehensive analysis of hospital-based cancer registry data (2000–2019). This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

Nearly all men with a polygenic risk score in the 90th percentile or above had a 10-year absolute risk for prostate cancer exceeding 3.8%. A polygenic risk score (PRS) identifies more patients with ...

Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly impairs women's quality of life, yet genetic insights into non-European ...

To the Editor: In the BARCODE1 study, McHugh et al. (April 10 issue) 1 assessed the use of a polygenic risk score in prostate cancer screening, concluding that more clinically significant cases were ...