A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the ...
Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by ...
Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator ...
Global proteomics and functional analyses reveal that p53-induced ZMAT3 suppresses mitochondrial respiration by inhibiting transcription of a hexokinase, uncovering a role for ZMAT3 in transcription.
The protein p53, best known as the "guardian of the genome" for its role in preventing cancer, can affect blood vessels in different ways. However, it has not been clear how p53 can slow blood vessel ...
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