Lysine methylation is a pivotal post‐translational modification that modulates protein function by the addition of methyl groups to the ε‐amine of lysine residues. This modification, catalysed by ...

Key modifications involved in HCC include lysine methylation and acetylation, regulated by KMTs/KDMs and HATs/HDACs, respectively, which influence chromatin accessibility and transcriptional activity.

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Histone Kla regulates tumor angiogenesis by affecting the levels of downstream HIF1-ɑ and Vegf. In non-histone proteins, YY1-Kla influences FGF2, and Sema3A-Kla affects HIF1-ɑ, both contributing to ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...