Aided by two molecular control factors, the spliceosome rejects pre-mRNA that could be incorrectly spliced. While GPATCH1 detects the defective pre-mRNA, DHX35 removes it from the spliceosome, which ...
The human genome is just over 6 feet 8 inches long, which is 2 inches taller than the average NBA basketball player and in total, a lot of nucleotides! But what if the amount of sequence diversity ...
Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...
A research team led by Prof. XUE Yuanchao from the Institute of Biophysics of the Chinese Academy of Sciences has developed a new method for global profiling of in-situ RNA–RNA contacts associated ...
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