Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to be associated with neurodegenerative disorders. Corresponding author Kai ...

Insulin is one of the most potent and pleiotropic hormones in the body, regulating a myriad of physiological processes. However, perhaps none is best studied as its role in regulating glucose ...

The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One of the insulin-regulated processes is the quality control of mitochondria in neurons, ...

Insulin signalling underpins the regulation of metabolic homeostasis, growth and cellular survival. At its core is the insulin receptor (IR), a covalent αβ₂ homodimeric tyrosine kinase that undergoes ...

Researchers from the German Diabetes Center (DDZ) and the Heinrich Heine University Düsseldorf (HHU) have studied the temporal pattern of insulin action on protein kinases in human muscle cells in ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

In 2021, a research team discovered the insulin-inhibitory receptor 'Inceptor' and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more ...

A new review suggests palmitic acid in saturated fats may impair insulin response, while oleic acid in olive oil may help ...

People with diabetes who depend on insulin face a sharply higher chance of developing dementia than those managing the ...

Not all fats affect your body the same way. Researchers found that palmitic acid, a saturated fat common in many foods, may ...