EU regulators have released for public consultation a guideline under development by the International Conference on Harmonisation (ICH) intended to establish the best practices for controlling ...

Forbes contributors publish independent expert analyses and insights. Emily Earlenbaugh covers cannabis science and culture. As cannabis legalization continues to increase globally, researchers are ...

CRISPR-Cas9 gene editing relies on a guide RNA that binds to a desired DNA sequence and a Cas9 enzyme that cuts both strands of DNA at that site, creating a double-strand break. Scientists edit the ...

Less than 60 minutes after his latest report was published online, Luigi Naldini, MD, PhD, called me to discuss his article, “Genotoxic effects of base and prime editing in human hematopoietic stem ...

There is no way to know whether the characteristics are truly unique to carcinogens by only including carcinogenic chemicals. A study examining the KCC approach found that the ability to predict ...

Genotoxic insults drive divergent outcomes in melanocyte stem cells (McSCs). Under cytotoxic genotoxin exposure, such as X-ray irradiation, McSC self-renewal is impaired, leading to depletion and hair ...