For the roughly 40 million Americans who swallow a statin pill every morning, the routine is simple but relentless: miss ...

With just one shot, scientists have slashed cholesterol levels in mice. The treatment lasted for at least half their lives. The shot may sound like gene editing, but it’s not. Instead, it relies on an ...

Novel CRISPR-Cas9 treatments are proving effective in reversing disease for life. But ensuring their long-term safety will ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. Gene-silencing therapies may finally be able to reach hard-to-target organs like the brain ...

In a recent study published in the journal Nature, scientists used mouse models to test whether in vivo gene silencing is sustained after transient delivery and expression of engineered ...

Mouse data from a new study published Feb. 28 in Nature and sponsored in part by Chroma Medicine suggest that epigenetic gene silencing can suppress the target gene for nearly a year, providing new ...

Epigenetics, the dynamic regulation of genetic expression, involves complex molecular mechanisms. While the process of gene silencing by methylating the H3K27 position in histones is understood, not ...

Silence Therapeutics designs and develops siRNAs (short interfering RNAs) to address unmet patient need across a wide range of diseases with a genetic basis. In this interview with STAT Brand Studio, ...

RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and ...

About half of all adults prescribed a statin stop taking it within a year. They forget, they dislike the side effects, or ...