Latin name: Ovis aries. Breed is unknown. Sheep are the most widely distributed domestic animal around the world. There are more than 200 breeds and they are raised for their wool, meat and milk. This ...

A new study suggests the APOE2 longevity gene may protect the brain from Alzheimer's by helping neurons repair DNA damage and ...

People who carry the APOE2 version of the apolipoprotein E gene are more likely to live to advanced age and are partly ...

Alzheimer’s may be driven far more by genetics than previously thought, with one gene playing an outsized role. Researchers found that up to nine in ten cases could be linked to the APOE gene — even ...

As resident trash collectors, microglia survey the brain in search of detritus for disposal. How do they recognize the debris? In the case of plaques, a cell-surface receptor might be involved, though ...

A groundbreaking study reveals how a single gene variant shapes the immune landscape of the brain and blood, unlocking new opportunities for early detection and intervention across Alzheimer’s, ...

The APOE region or locus is a segment of DNA with several genes in close apposition, including APOE. Its boundaries are not strictly defined, spanning a stretch between 0.2 and 10 Mb long. In 5’ to 3’ ...

The APOE2 gene variant protects against Alzheimer's by enhancing DNA repair and preventing neuronal senescence.

Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers. The scientists also found ...