While the large proportion of our genome that does not instruct our cells to form proteins has been harder to study than protein-coding genes, it has been shown to have vital physiological functions.

What happens when a scientific problem seems too complex to solve precisely, yet understanding it could reshape how researchers design new materials and medicines? For decades, much of the polymer ...

The effects of sequence variation on function are elucidated by a study of protein evolution. Experimental studies using deep mutational scanning can address epistasis for low-order combinations at ...

Deep learning approaches have transformed how scientists predict the activity and function of DNA sequences in the genome. A ...

The expression pattern of a single gene or multiple genes can be investigated using a technique RNA microarray. In this technique, RNA molecules are ‘spotted’ onto a solid surface. These act as probes ...