Focal adhesions are dynamic multi-protein assemblies that anchor the intracellular actin cytoskeleton to the extracellular matrix, thereby converting mechanical stimuli into biochemical signals.

S100A11 is a small Ca 2+-activatable protein with an established role in different cellular processes involving actin cytoskeleton remodeling, such as cell migration, membrane protrusion formation, ...

The fight against cancer often begins with uncovering hidden players, and a recent study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in ...

Focal adhesion kinase (FAK) is a central regulator of how cells sense and respond to their surroundings. Situated at integrin-based adhesions, FAK transmits signals from the extracellular matrix and ...

Immunofluorescence image showing S100A11 (green) localization to focal adhesions and actin stress fibers in a HeLa cell. Microtubules are labeled in red. Researchers at Kanazawa University report in ...