New study reveals how mass spectrometry can be used to determine the mechanisms used by molecular glues to stick to their targets. Molecular glues are a continually expanding area of medicinal ...

Template-assisted synthesis dramatically improves the yield of functionalized oligophenylene cages, report researchers from Japan. By using covalent templates to guide a six-fold Suzuki–Miyaura ...

Researchers efficiently synthesize functionalized oligophenylene cages using covalent templates and cooperative intermolecular coupling. (Nanowerk News) Template-assisted synthesis dramatically ...

Note: This video is designed to help the teacher better understand the lesson and is NOT intended to be shown to students. It includes observations and conclusions that students are meant to make on ...

Although covalent drugs have been used for more than a century, the emergence of new tools has helped spur recent advances in the field. Indeed, covalent medicine experienced a resurgence roughly 15 ...

Misbehaving proteins are behind many diseases. One way drugmakers incapacitate these bad actors is to deploy molecules that bind to them. But finding solid footholds on the proteins to block their ...