For decades, treating major depression has involved a frustrating cycle of trial and error, with patients cycling through medications and therapies while clinicians rely on symptoms and intuition more ...

Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. However, only Yueju Pill increased a brain-supporting ...

A new randomized clinical trial from investigators at Mass General Brigham’s Neuroscience Institute and Department of ...

Depression is a mental health disorder characterized by a recurrent or persistent sadness and a loss of interest in activities that were previously deemed pleasurable, sometimes accompanied by changes ...

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...