A part of the apoferritin protein (yellow) with a tyrosine side chain highlighted in grey. The amino acid tyrosine consists of several atoms that are individually recognizable in the structure (red ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

Cryo-electron microscopy (cryo-EM) has profoundly reshaped our understanding of biomolecular structures by allowing the direct imaging of macromolecules in near-native states. This technique, which ...

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

A custom-designed electron cryomicroscope operating at 100 keV promises to minimize the expense and complexity of biological structure research. Although electron cryo-microscopy (cryo-EM) has shown ...

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists from the ...

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly ...

The Cryo-Electron Microscopy Center supports industry, academic, government, and non-profit research institutes, providing single-particle and microcrystal electron diffraction capabilities. We offer ...

Surface model of SpCas9–reverse transcriptase–pegRNA–target DNA complex. The prime editor, composed of a SpCas9 and a reverse transcriptase, reverse transcribes template sequence in pegRNA, resulting ...