A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
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Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
Two sets of ribosome structures have recently led to two different interpretations of what limits the accuracy of codon translation by transfer RNAs. In this review, inspired by this intermezzo at the ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 26 (Jun. 26, 2007), pp. 10824-10829 (6 pages) In universal-code eukaryotes, a single-translation ...
DNA has often been called “the book of life,” but this popular phrase makes some biologists squirm a bit. True, DNA bears our genes, which spell out the instructions our cells use to make ...
The genetic code is a set of instructions that direct the translation of DNA into 20 amino acids, the basic units of proteins in living cells. The genetic code is made up of codons, which are ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
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