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DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli
A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
Combining MAGE with CAGE allowed the genome to manipulated as an editable and evolvable template. Scientists have combined a recently developed technique known as multiplex automated genome ...
We have gone further than ever before in creating life that is unlike anything that has evolved naturally. The genome of an Escherichia coli bacterium has been redesigned on a computer to use just 57 ...
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An illustration of E. coli. Scientists have been racing to shrink the genetic code of this bacterium. Kateryna Kon / Science Photo Library via Getty Images The DNA of nearly all life on Earth is made ...
The DNA of nearly all life on Earth contains many redundancies, and scientists have long wondered whether these redundancies served a purpose or if they were just leftovers from evolutionary processes ...
A team of investigators at The Scripps Research Institute and its Skaggs Institute for Chemical Biology in La Jolla, California has modified a form of the bacterium Escherichia coli to use a 22-amino ...
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