Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...

Researchers looked specifically at head-to-head randomized clinical trials of next-in-class cancer drugs against existing agents in the same class. Less than one-quarter of next-in-class cancer drugs ...

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 is targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...

Individuals with HIV who were resistant to all four antiretroviral drug classes experienced higher mortality than those who were not resistant, a difference primarily due to lower CD4 cell counts.

An investigational drug previously shown to improve wakefulness and reduce sleepiness in patients with narcolepsy type 1 (NT1) has now been linked to improved cognition. After 8 weeks of treatment, ...