Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and ...

To test the hypothesis that patients with hypoplastic left heart syndrome (HLHS) and developmental delay will have a higher average summative C-score in ciliopathy genes than patients with HLHS ...

Almost every eukaryotic cell type has cilia—tiny hairlike structures—on their surface. But, the function of cilia is not well understood. Now, researchers show that human pluripotent stem cells (hPSCs ...

A group of rare diseases called ciliopathies -- polycystic kidney disease notable among them -- emerge from defects in cilia. These are the tiny hairlike structures on the surface of almost every cell ...

The Nature Index tracks primary research articles from 145 natural-science and health-science journals, chosen based on reputation by an independent group of researchers. The Nature Index provides ...

A large study of Saudi patients reveals new genetic causes of disorders associated with dysfunctions in the cell’s ‘antenna’. Researchers in Saudi Arabia identified dozens of new mutations in 54 genes ...

New disease called "TULP3-related ciliopathy" has been discovered and the treatment of which would help patients with unexplained liver and kidney problems. There are numerous reasons for kidney and ...

Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE) ...

Scientists have identified a new disease in a ground-breaking discovery that could help patients with unexplained liver and kidney problems. Experts at Newcastle University, UK, have established the ...

Scientists at Newcastle University in the United Kingdom have discovered an inherited condition called TULP3-related ciliopathy that causes kidney and liver failure in children and adults. There are ...