A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer's, cystic fibrosis, and cancer. But there are about 70,000 different proteins and protein variants ...

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

Protein aggregates, damaged organelles, and invading bacteria are identified and removed in healthy cells. An international ...

Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...

Spatial proteomics is the study of the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular function, making spatial ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.