New model extracts stiffness and fluidity from AFM data in minutes, enabling fast, accurate mechanical characterization of living cells at single-cell resolution. (Nanowerk Spotlight) Cells are not ...

The study of biological systems varies from whole organisms, organs, and organoids, down to their building blocks of proteins and cells. At the lower end of the scale, atomic force microscope (AFM) ...

A research team has developed a technology that distinguishes lung cancer gene mutations solely by measuring the "stiffness" of exosomes—tiny particles released from cancer cells in the ...

AFM is a scanning probe microscopic instrument that consists of a force-sensing microcantilever, a laser source, a piezoelectric scanner and a photodiode detector (Figure 1A). During AFM imaging, the ...

(Nanowerk News) Membrane rafts are nanometer-scale structures rich in cholesterol and sphingolipids, believed to serve as vital platforms for cell signaling, viral entry, and cancer metastasis. Since ...

Current optical and electron microscopy imaging techniques are not suited for measuring the dynamic characteristics of living microorganisms at tiny scales due to complex sample preparation methods or ...

Macrophages drive key immune processes including inflammation, tissue repair, and tumorigenesis via distinct polarization states whose accurate identification is vital for diagnosis and immunotherapy.

Our bodies comprise different tissues and organs, which are composed of many cells that must adhere to form functional higher order structures. This adherence is facilitated by specialized proteins ...

First invented in 1985 by IBM in Zurich, Atomic Force Microscopy (AFM) is a scanning probe technique for imaging. It involves a nanoscopic tip attached to a microscopic, flexible cantilever, which is ...

Biomechanics reveals cell wall age properties and how newly born cells can change their local shape and influence the growth of plant organs Scientists reveal new plant cell walls can have ...