Host cell protein (HCP) analysis remains a pivotal aspect in the development and manufacture of biopharmaceuticals, ensuring that therapeutic products meet stringent quality and safety standards. HCPs ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

Cells do this by breaking proteins down and recycling them, a process summarily referred to as "protein removal." But this ongoing and vital "dance" of protein making and protein removal takes energy ...

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

Two recently published studies led by Brazilian scientists reveal the key roles of multifunctional proteins, STIP1 and Maspin, in vital cellular processes. The results demonstrate new protein ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living cells - using the cells' own components as built-in sensors. This approach could ...

Randomness inside cells can decide whether a cancer returns after chemotherapy or whether an infection survives antibiotics.