A new "tumor-on-a-chip" model is giving scientists a live look at how pancreatic cancer can recruit the body's own immune ...

According to the American Cancer Society, colorectal cancer is the second leading cause of cancer death. Enrichment of regulatory T cells (T-regs) in solid cancers is generally associated with poor ...

Scientists have discovered why ovarian cancer spreads so rapidly through the abdomen. Cancer cells enlist normally protective abdominal cells, forming mixed groups that work together to invade new ...

How do different cancer subtypes arise? Do they originate from distinct cells, or from a single multipotent cell capable of differentiating into multiple cell types? This question, debated for decades ...

Up to 20% of hormone receptor-positive breast cancers don't respond to antiestrogen therapies. A study led by researchers at UT Southwestern, published in the Journal of Clinical Investigation, ...

Study unveils how colon cancer cells change identity to spread ...

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others.

Cancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the ...