Biomarker testing for 11 oncogenes at diagnosis enables personalized lung cancer treatment, moving away from a one-size-fits-all approach. Biomarkers serve diagnostic, prognostic, and predictive roles ...
In oncology drug development, biomarker-driven studies are pivotal, enabling the selection of patient populations most likely to benefit from specific therapeutic interventions. These studies have ...
The risk for future incident mild cognitive impairment or dementia in older women was elevated with higher levels of plasma phosphorylated tau 217, according to data published in JAMA Network Open.“Ou ...
Tania Gendron, PhD, speaks to the present challenges for translating biomarker discoveries to clinical practice and offers insights to how these can be overcome. Biomarker exploration has been a ...
Persistence of high EBNA-1 titers across longitudinal samples was characteristic of MS, whereas MOGAD and NMOSD generally exhibited titer attenuation during follow-up. High-level EBNA-1 positivity in ...
A fully automated plasma biomarker panel detected amyloid-beta (Aβ) positivity and monitored early amyloid accumulation in middle-aged cognitively unimpaired (CU) adults at risk for Alzheimer's ...
A study spanning 20 years helps nail down the timing of biomarker changes that occur in the period between normal cognition and a diagnosis of sporadic Alzheimer's disease (AD), something that hasn't ...
Blood lactate levels were associated with survival and weight changes in ALS, according to a study in Australia and Japan.
Despite the clinical utility of biomarker testing in patients with prostate cancer, the tests are infrequently ordered, preventing optimized care. Despite guideline recommendations and the efficacy of ...
A personalized peptide vaccine slashed prostate-specific antigen levels by as much as 99.6% in some men with advanced prostate cancer, according to a phase II clinical trial conducted at Kurume ...