Three the approved drugs for Alzheimer’s disease attempt to boost the brain’s supply of acetylcholine, a critical neurotransmitter for cognition that wanes in people with the disease. But might ...

A new study shows inhibiting the kinase p38α using the small molecule drug neflamapimod, could potentially improve cognitive and motor function in patients with neurodegenerative diseases that affect ...

Cortical gamma band oscillations (GBO, 30–80 Hz, typically ∼40 Hz) are involved in higher cognitive functions such as feature binding, attention, and working memory. GBO abnormalities are a feature of ...

The ability of the brain to recover from such injury as stroke or trauma depends on a particular circuitry of neurons that "talk" to one another using the brain chemical acetylcholine, researchers led ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 8 (February 23, 2016), pp. E1089-E1097 (9 pages) The cortical cholinergic input system has been described ...

Markova TZ, Fonseca CS, Ciampa CJ, … & Berry, A. S. (2025). Defining the contributions of tau pathology in the amygdala to increasing depressive symptoms in aging ...