The mechanism of lipid-mediated phase separation of AGO proteins on the ER in regulating nascent-peptide ubiquitination. Credit: Chen lab The miRNA-mediated gene silencing and the ubiquitin-mediated ...

Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a ...

Korean researchers have uncovered the protein assembly mechanism that regulates gene expression, paving the way for the precise design of RNA treatments — with ...

Insects and plants have an important ancient defense mechanism that helps them to fight viruses. This is encoded in their DNA. Scientists have long assumed that vertebrates - including humans - also ...