The immune system of vertebrates is a powerful weapon against external pathogens and cancerous cells. T cells play a crucial role in this context. They carry a special receptor called the T-cell ...
A cell's secrets can be divulged by its surface, decorated with tens to hundreds of thousands of molecules that help immune cells determine friend from foe. Some of those protruding molecules are ...
Real-world treatment patterns in patients with BRCA 1/2-positive (BRCA+) metastatic castration-resistant prostate cancer (mCRPC) initiating first-line (1L) therapy.
Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly ...
Why is plinabulin important for immuno-oncology? Plinabulin is a potent activator of GEF-H1, an immune defense protein that drives dendritic cell (DC) maturation, antigen cross-presentation and ...
The seasonal influenza vaccine contains strains of viruses from distinct virus subtypes, but most people who are vaccinated will mount a strong immune response to one strain, leaving them vulnerable ...
It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...
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