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Cinchona alkaloids have a long and storied history in chemistry. Derived from Cinchona plants, members of the molecular family include the chiral catalyst cinchonidine and quinine, an early ...

Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines. Alkaloids are typically polycyclic in ...

The club moss Lycopodium serratum is a creeping, flowerless plant used in homeopathic medicine to treat a wide variety of ailments. It contains a potent brew of alkaloids that have attracted ...

What does cannabis, coca leaf, and all coffee have in common? They all contain alkaloids, a powerful group of medicinal compounds found in plants around the world. While little is presently known ...

A step forward in our understanding of how plants produce alkaloids could herald new pharmaceuticals. Biologists from the University of York (UK) have discovered enzymes that catalyze the biosynthesis ...

Camellia ptilophylla, a low-caffeine or decaffeinated tea, is increasingly being recognized for its potential health benefits. However, there is intraspecific diversity in purine alkaloid and ...

Benzylisoquinoline alkaloids (BIAs) represent a diverse group of plant secondary metabolites that are of profound pharmacological importance. These compounds, which include opiates, antimicrobial ...

Complex polycylic structures are found in nearly every biosynthetic class of natural products. In particular, an amazing range of rigid densely functionalized polycylic compounds are formed from ...

Making chemical handles that latch onto amino acids is a strategy used to make covalent drugs, antibody-drug conjugates, and biochemical probes. Cysteine and lysine are common points of attachment, ...